Publikationen von E Izaurralde

Xia, S.; Ventura, I.; Blaha, A.; Sgromo, A.; Han, S.; Izaurralde, E.; Long, M.: Rapid Gene Evolution in an Ancient Post-transcriptional and Translational Regulatory System Compensates for Meiotic X Chromosomal Inactivation. Molecular Biology and Evolution 39 (1), msab296 (2022)

Chen, Y.; Khazina, E.; Izaurralde, E.; Weichenrieder, O.: Crystal structure and functional properties of the human CCR4-CAF1 deadenylase complex. Nucleic Acids Research (London) 49 (11), S. 6489 - 6510 (2021)

Weber, R.; Chung, M.-Y.; Keskeny, C.; Zinnall, U.; Landthaler, M.; Valkov, E.; Izaurralde, E.; Igreja, C.: 4EHP and GIGYF1/2 Mediate Translation-Coupled Messenger RNA Decay. Cell Reports 33 (2), 108262 (2020)

Räsch, F.; Weber, R.; Izaurralde, E.; Igreja, C.: 4E-T-bound mRNAs are stored in a silenced and deadenylated form. Genes and Development 34 (11-12), S. 847 - 860 (2020)

Peter, D.; Ruscica, V.; Bawankar, P.; Weber, R.; Helms, S.; Valkov, E.; Igreja, C.; Izaurralde, E.: Molecular basis for GIGYF-Me31B complex assembly in 4EHP-mediated translational repression. Genes and Development 33 (19-20), S. 1355 - 1360 (2019)

Chang, C.-T.; Muthukumar, S.; Weber, R.; Levdansky, Y.; Chen, Y.; Bhandari, D.; Igreja, C.; Wohlbold, L.; Valkov, E.; Izaurralde, E.: A low-complexity region in human XRN1 directly recruits deadenylation and decapping factors in 5'-3' messenger RNA decay. Nucleic Acids Research (London) 47 (17), S. 9282 - 9295 (2019)

Ruscica, V.; Bawankar, P.; Peter, D.; Helms, S.; Igreja, C.; Izaurralde, E.: Direct role for the Drosophila GIGYF protein in 4EHP-mediated mRNA repression. Nucleic Acids Research (London) 47 (13), S. 7035 - 7048 (2019)

Keskeny, C.; Raisch, T.; Sgromo, A.; Igreja, C.; Bhandari, D.; Weichenrieder, O.; Izaurralde, E.: A conserved CAF40-binding motif in metazoan NOT4 mediates association with the CCR4-NOT complex. Genes and Development 33 (3-4), S. 236 - 252 (2019)

Raisch, T.; Sandmeir, F.; Weichenrieder, O.; Valkov, E.; Izaurralde, E.: Structural and biochemical analysis of a NOT1 MIF4G-like domain of the CCR4-NOT complex. Journal of Structural Biology 204 (3), S. 388 - 395 (2018)

Grüner, S.; Weber, R.; Peter, D.; Chung, M.-Y.; Igreja, C.; Valkov, E.; Izaurralde, E.: Structural motifs in eIF4G and 4E-BPs modulate their binding to eIF4E to regulate translation initiation in yeast. Nucleic Acids Research (London) 46 (13), S. 6893 - 6908 (2018)

Sgromo, A.; Raisch, T.; Backhaus, C.; Keskeny, C.; Alva, V.; Weichenrieder, O.; Izaurralde, E.: Drosophila Bag-of-marbles directly interacts with the CAF40 subunit of the CCR4-NOT complex to elicit repression of mRNA targets. RNA-A Publication of the RNA Society 24 (3), S. 381 - 395 (2018)

Peter, D.; Weber, R.; Sandmeir, F.; Wohlbold, L.; Helms, S.; Bawankar, P.; Valkov, E.; Igreja, C.; Izaurralde, E.: GIGYF1/2 proteins use auxiliary sequences to selectively bind to 4EHP and repress target mRNA expression. Genes and Development 31 (11), S. 1147 - 1161 (2017)

Sgromo, A.; Raisch, T.; Bawankar, P.; Bhandari, D.; Chen, Y.; Kuzuoğlu-Öztürk, D.; Weichenrieder, O.; Izaurralde, E.: A CAF40-binding motif facilitates recruitment of the CCR4-NOT complex to mRNAs targeted by Drosophila Roquin. Nature Communications 8, 14307 (2017)

Grüner, S.; Peter, D.; Weber, R.; Wohlbold, L.; Chung, M.-Y.; Weichenrieder, O.; Valkov, E.; Igreja, C.; Izaurralde, E.: The Structures of eIF4E-eIF4G Complexes Reveal an Extended Interface to Regulate Translation Initiation. Molecular Cell 64 (3), S. 467 - 479 (2016)

Kuzuoğlu-Öztürk, D.; Bhandari, D.; Huntzinger, E.; Fauser, M.; Helms, S.; Izaurralde, E.: miRISC and the CCR4-NOT complex silence mRNA targets independently of 43S ribosomal scanning. EMBO Journal 35 (11), S. 1186 - 1203 (2016)

Valkov, E.; Muthukumar, S.; Chang, C.-T.; Jonas, S.; Weichenrieder, O.; Izaurralde, E.: Structure of the Dcp2-Dcp1 mRNA-decapping complex in the activated conformation. Nature Structural and Molecular Biology 23 (6), S. 574 - 579 (2016)

Raisch, T.; Bhandari, D.; Sabath, K.; Helms, S.; Valkov, E.; Weichenrieder, O.; Izaurralde, E.: Distinct modes of recruitment of the CCR4-NOT complex by Drosophila and vertebrate Nanos. EMBO Journal 35 (9), S. 974 - 990 (2016)

Peter, D.; Weber, R.; Köne, C.; Chung, M.-Y.; Ebertsch, L.; Truffault, V.; Weichenrieder, O.; Igreja, C.; Izaurralde, E.: Mextli proteins use both canonical bipartite and novel tripartite binding modes to form eIF4E complexes that display differential sensitivity to 4E-BP regulation. Genes and Development 29 (17), S. 1835 - 1849 (2015)

Izaurralde, E.: Breakers and blockers: miRNAs at work. Science 39 (6246), S. 380 - 382 (2015)

Jonas, S.; Izaurralde, E.: Towards a molecular understanding of microRNA-mediated gene silencing. Nature Reviews Genetics 16 (7), S. 421 - 433 (2015)