Publications of E Huntzinger

Kuzuoğlu-Öztürk, D.; Bhandari, D.; Huntzinger, E.; Fauser, M.; Helms, S.; Izaurralde, E.: miRISC and the CCR4-NOT complex silence mRNA targets independently of 43S ribosomal scanning. EMBO Journal 35 (11), pp. 1186 - 1203 (2016)

Jonas, S.; Christie, M.; Peter, D.; Bhandari, D.; Loh, B.; Huntzinger, E.; Weichenrieder, O.; Izaurralde, E.: An asymmetric PAN3 dimer recruits a single PAN2 exonuclease to mediate mRNA deadenylation and decay. Nature Structural and Molecular Biology 21 (7), pp. 599 - 608 (2014)

Christie, M.; Boland, A.; Huntzinger, E.; Weichenrieder, O.; Izaurralde, E.: Structure of the PAN3 pseudokinase reveals the basis for interactions with the PAN2 deadenylase and the GW182 proteins. Molecular Cell 5 (3), pp. 360 - 373 (2013)

Huntzinger, E.; Kuzuoğlu-Öztürk, D.; Braun, J.; Eulalio, A.; Wohlbold, L.; Izaurralde, E.: The interactions of GW182 proteins with PABP and deadenylases are required for both translational repression and degradation of miRNA targets. Nucleic Acids Research (London) 41 (2), pp. 978 - 994 (2013)

Braun, J.; Huntzinger, E.; Izaurralde, E.: A molecular link between miRISCs and deadenylases provides new insight into the mechanism of gene silencing by microRNAs. Cold Spring Harbor Perspectives in Biology 4 (12), a012328 (2012)

Braun, J.; Truffault, V.; Boland, A.; Huntzinger, E.; Chang, C.-T.; Haas, G.; Weichenrieder, O.; Coles, M.; Izaurralde, E.: A direct interaction between DCP1 and XRN1 couples mRNA decapping to 5' exonucleolytic degradation. Nature Structural and Molecular Biology 19 (12), pp. 1324 - 1331 (2012)

Petit, A.-P.; Wohlbold, L.; Bawankar, P.; Huntzinger, E.; Schmidt, S.; Izaurralde, E.; Weichenrieder, O.: The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complex. Nucleic Acids Research (London) 40 (21), pp. 11058 - 11072 (2012)

Kuzuoğlu-Öztürk, D.; Huntzinger, E.; Schmidt, S.; Izaurralde, E.: The Caenorhabditis elegans GW182 protein AIN-1 interacts with PAB-1 and subunits of the PAN2-PAN3 and CCR4-NOT deadenylase complexes. Nucleic Acids Research (London) 40 (12), pp. 5651 - 5665 (2012)

Braun, J.; Huntzinger, E.; Fauser, M.; Izaurralde, E.: GW182 proteins directly recruit cytoplasmic deadenylase complexes to miRNA targets. Molecular Cell 44 (1), pp. 120 - 133 (2011)

Boland, A.; Huntzinger, E.; Schmidt, S.; Izaurralde, E.; Weichenrieder, O.: Crystal structure of the MID-PIWI lobe of a eukaryotic Argonaute protein. Proceedings of the National Academy of Sciences of the United States of America 108 (26), pp. 10466 - 10471 (2011)

Huntzinger, E.; Izaurralde, E.: Gene silencing by microRNAs: contributions of translational repression and mRNA decay. Nature Reviews Genetics 12 (2), pp. 99 - 110 (2011)

Huntzinger, E.; Braun, J.; Heimstädt, S.; Zekri, L.; Izaurralde, E.: Two PABPC1-binding sites in GW182 proteins promote miRNA-mediated gene silencing. EMBO Journal 29 (24), pp. 4146 - 4160 (2010)

Tritschler, F.; Huntzinger, E.; Izaurralde, E.: Role of GW182 proteins and PABPC1 in the miRNA pathway: a sense of déjà vu. Nature Reviews Molecular Cell Biology 11 (5), pp. 379 - 384 (2010)

Zekri, L.; Huntzinger, E.; Heimstädt, S.; Izaurralde, E.: The silencing domain of GW182 interacts with PABPC1 to promote translational repression and degradation of microRNA targets and is required for target release. Molecular and Cellular Biology (Washington, DC) 29 (23), pp. 6220 - 6231 (2009)

Wittkopp, N.; Huntzinger, E.; Weiler, C.; Saulière, J.; Schmidt, S.; Sonawane, M.; Izaurralde, E.: Nonsense-mediated mRNA decay effectors are essential for zebrafish embryonic development and survival. Molecular and Cellular Biology (Washington, DC) 29 (13), pp. 3517 - 3528 (2009)

Eulalio, A.; Huntzinger, E.; Nishihara, T.; Rehwinkel, J.; Fauser, M.; Izaurralde, E.: Deadenylation is a widespread effect of miRNA regulation. RNA: A Publication of the RNA Society 15 (1), pp. 21 - 32 (2009)

Huntzinger, E.; Kashima, I.; Fauser, M.; Saulière, J.; Izaurralde, E.: SMG6 is the catalytic endonuclease that cleaves mRNAs containing nonsense codons in metazoan. RNA: A Publication of the RNA Society 14 (12), pp. 2609 - 2617 (2008)

Eulalio, A.; Huntzinger, E.; Izaurralde, E.: GW182 interaction with Argonaute is essential for miRNA-mediated translational repression and mRNA decay. Nature Structural and Molecular Biology 15 (4), pp. 346 - 353 (2008)

Eulalio, A.; Huntzinger, E.; Izaurralde, E.: Getting to the root of miRNA-mediated gene silencing. Cell 132 (1), pp. 9 - 14 (2008)

Eulalio, A.; Rehwinkel, J.; Stricker, M.; Huntzinger, E.; Yang, S.-F.; Doerks, T.; Dorner, S.; Bork, P.; Boutros, M.; Izaurralde, E.: Target-specific requirements for enhancers of decapping in miRNA-mediated gene silencing. Genes and Development 2 (20), pp. 2558 - 2570 (2007)