Publications of JE Braun

Nishihara, T.; Zekri, L.; Braun, J.; Izaurralde, E.: miRISC recruits decapping factors to miRNA targets to enhance their degradation. Nucleic Acids Research (London) 41 (18), pp. 8692 - 8705 (2013)

Huntzinger, E.; Kuzuoğlu-Öztürk, D.; Braun, J.; Eulalio, A.; Wohlbold, L.; Izaurralde, E.: The interactions of GW182 proteins with PABP and deadenylases are required for both translational repression and degradation of miRNA targets. Nucleic Acids Research (London) 41 (2), pp. 978 - 994 (2013)

Braun, J.; Huntzinger, E.; Izaurralde, E.: A molecular link between miRISCs and deadenylases provides new insight into the mechanism of gene silencing by microRNAs. Cold Spring Harbor Perspectives in Biology 4 (12), a012328 (2012)

Braun, J.; Truffault, V.; Boland, A.; Huntzinger, E.; Chang, C.-T.; Haas, G.; Weichenrieder, O.; Coles, M.; Izaurralde, E.: A direct interaction between DCP1 and XRN1 couples mRNA decapping to 5' exonucleolytic degradation. Nature Structural and Molecular Biology 19 (12), pp. 1324 - 1331 (2012)

Fromm, S.; Truffault, V.; Kamenz, J.; Braun, J.; Hoffmann, N.; Izaurralde, E.; Sprangers, R.: The structural basis of Edc3- and Scd6-mediated activation of the Dcp1:Dcp2 mRNA decapping complex. EMBO Journal 31 (2), pp. 279 - 290 (2012)

Braun, J.; Huntzinger, E.; Fauser, M.; Izaurralde, E.: GW182 proteins directly recruit cytoplasmic deadenylase complexes to miRNA targets. Molecular Cell 44 (1), pp. 120 - 133 (2011)

Huntzinger, E.; Braun, J.; Heimstädt, S.; Zekri, L.; Izaurralde, E.: Two PABPC1-binding sites in GW182 proteins promote miRNA-mediated gene silencing. EMBO Journal 29 (24), pp. 4146 - 4160 (2010)

Braun, J.; Tritschler, F.; Haas, G.; Igreja, C.; Truffault, V.; Weichenrieder, O.; Izaurralde, E.: The C‐terminal α–α superhelix of Pat is required for mRNA decapping in metazoa. EMBO Journal 29 (14), pp. 2368 - 2380 (2010)

Haas, G.; Braun, J.; Igreja, C.; Tritschler, F.; Nishihara, T.; Izaurralde, E.: HPat provides a link between deadenylation and decapping in metazoa. The Journal of Cell Biology: JCB 189 (2), pp. 289 - 302 (2010)

Tritschler, F.; Braun, J.; Motz, C.; Igreja, C.; Haas, G.; Truffault, V.; Izaurralde, E.; Weichenrieder, O.: DCP1 forms asymmetric trimers to assemble into active mRNA decapping complexes in metazoa. Proceedings of the National Academy of Sciences of the United States of America 106 (51), pp. 21591 - 21596 (2009)

Tritschler, F.; Braun, J.; Eulalio, A.; Truffault, V.; Izaurralde, E.; Weichenrieder, O.: Structural basis for the mutually exclusive anchoring of P body components EDC3 and Tral to the DEAD box protein DDX6/Me31B. Molecular Cell 33 (5), pp. 661 - 668 (2009)

Braun, J.; Huntzinger, E.; Izaurralde, E.: The role of GW182 proteins in miRNA-mediated gene silencing. In: Advances in Experimental Medicine and Biology, Vol. 768. Plenum Press, New York (2013)

Braun, J.; Huntzinger, E.; Zekri, L.; Izaurralde, E.: Dissecting the molecular mechanisms of miRNA-mediated gene silencing. 4th Berlin Summer Meeting: “Computational & Experimental Molecular Biology Meet”, Berlin, Germany (2011)

Braun, J.: Der Mechanismus des microRNA-vermittelten mRNA-Abbaus: Mechanism of microRNA-mediated mRNA Decay. Dissertation, Eberhard-Karls-Universität, Tübingen, Germany (2012)