Publications of R Sprangers

Fuchs, A.-L.; Wurm, J.; Neu, A.; Sprangers, R.: Molecular basis of the selective processing of short mRNA substrates by the DcpS mRNA decapping enzyme. Proceedings of the National Academy of Sciences of the United States of America 117 (32), pp. 19237 - 19244 (2020)

Fraga, H.; Arnaud, C.-A.; Gauto, D.; Audin, M.; Kurauskas, V.; Macek, P.; Krichel, C.; Guan, J.-Y.; Boisbouvier, J.; Sprangers, R. et al.; Breyton, C.; Schanda, P.: Solid-State NMR H-N-(C)-H and H-N-C-C 3D/4D Correlation Experiments for Resonance Assignment of Large Proteins. ChemPhysChem 18 (19), pp. 2697 - 2703 (2017)

Schütz, S.; Nöldeke, E.; Sprangers, R.: A synergistic network of interactions promotes the formation of in vitro processing bodies and protects mRNA against decapping. Nucleic Acids Research (London) 45 (11), pp. 6911 - 6922 (2017)

Wurm, J.; Holdermann, I.; Overbeck, J.; Mayer, P.; Sprangers, R.: Changes in conformational equilibria regulate the activity of the Dcp2 decapping enzyme. Proceedings of the National Academy of Sciences of the United States of America 114 (23), pp. 6034 - 6039 (2017)

Heim, J.; Squirewell, E.; Neu, A.; Zocher, G.; Sominidi-Damodaran, S.; Wyles, S.; Nikolova, E.; Behrendt, N.; Saunte, D.; Lock-Andersen, J. et al.; Gaonkar, K.; Yan, H.; Sarkaria, J.; Krendel, M.; van Deursen, J.; Sprangers, R.; Stehle, T.; Boettcher, R.; Lee, J.-H.; Ordog, T.; Meves, A.: Myosin-1E interacts with FAK proline-rich region 1 to induce fibronectin-type matrix. Proceedings of the National Academy of Sciences of the United States of America 114 (15), pp. 3933 - 3938 (2017)

Cvetkovic, M.; Wurm, J.; Audin, M.; Schütz, S.; Sprangers, R.: The Rrp4-exosome complex recruits and channels substrate RNA by a unique mechanism. Nature Chemical Biology 13 (5), pp. 522 - 528 (2017)

Fuchs, A.-L.; Neu, A.; Sprangers, R.: A general method for rapid and cost-efficient large-scale production of 5' capped RNA. RNA 22 (9), pp. 1454 - 1466 (2016)

Wurm, J.; Overbeck, J.; Sprangers, R.: The S. pombe mRNA decapping complex recruits cofactors and an Edc1-like activator through a single dynamic surface. RNA 22 (9), pp. 1360 - 1372 (2016)

Audin, M.; Wurm, J.; Cvetkovic, M.; Sprangers, R.: The oligomeric architecture of the archaeal exosome is important for processive and efficient RNA degradation. Nucleic Acids Research (London) 44 (6), pp. 2962 - 2973 (2016)

Stützer, A.; Liokatis, S.; Kiesel, A.; Schwarzer, D.; Sprangers, R.; Söding, J.; Selenko, P.; Fischle, W.: Modulations of DNA contacts by linker histones and post-translational modifications determine the mobility and modifiability of nucleosomal H3 tails. Molecular Cell 61 (2), pp. 247 - 259 (2016)

Neu, A.; Neu, U.; Fuchs, A.-L.; Schlager, B.; Sprangers, R.: An excess of catalytically required motions inhibits the scavenger decapping enzyme. Nature Chemical Biology 11 (9), pp. 697 - 704 (2015)

Sprangers, R.: The sum is more than the parts: crystal and solution data reveal that the PIDDosome core complex is a dynamic assembly. Journal of Molecular Biology 427 (4), pp. 715 - 717 (2015)

Wiesner, S.; Sprangers, R.: Methyl groups as NMR probes for biomolecular interactions. Current Opinion in Structural Biology 35, pp. 60 - 67 (2015)

Fromm, S.; Kamenz, J.; Nöldeke, E.; Neu, A.; Zocher, G.; Sprangers, R.: In vitro reconstitution of a cellular phase-transition process that involves the mRNA decapping machinery. Angewandte Chemie, International Edition in English 53 (28), pp. 7354 - 7359 (2014)

Mund, M.; Overbeck, J.; Ullmann, J.; Sprangers, R.: LEGO-NMR spectroscopy: a method to visualize individual subunits in large heteromeric complexes. Angewandte Chemie, International Edition in English 52 (43), pp. 11401 - 11405 (2013)

Audin, M.; Dorn, G.; Fromm, S.; Reiss, K.; Schütz, S.; Vorländer, M.; Sprangers, R.: The archaeal exosome: identification and quantification of site-specific motions that correlate with cap and RNA binding. Angewandte Chemie, International Edition in English 52 (32), pp. 8312 - 8316 (2013)

Fromm, S.; Truffault, V.; Kamenz, J.; Braun, J.; Hoffmann, N.; Izaurralde, E.; Sprangers, R.: The structural basis of Edc3- and Scd6-mediated activation of the Dcp1:Dcp2 mRNA decapping complex. EMBO Journal 31 (2), pp. 279 - 290 (2012)

Mund, M.; Neu, A.; Ullmann, J.; Neu, U.; Sprangers, R.: Structure of the LSm657 Complex: An Assembly Intermediate of the LSm1-7 and LSm2-8 Rings. Journal of Molecular Biology (London) 414 (2), pp. 165 - 176 (2011)

Overbeck, J.; Wurm, J.; Holdermann, I.; Mayer, P.; Sprangers, R.: Simulation of PRE data for flexible ATCUN and TEMPO spin labels in decapping complexes. In Annual European Magnetic Resonance Meeting (Euromar 2017), p. 55. Annual European Magnetic Resonance Meeting (Euromar 2017), Warszawa, Poland, July 02, 2017 - July 06, 2017. (2017)

Wurm, J.; Holdermann, I.; Overbeck, J.; Mayer, P.; Sprangers, R.: Conformational landscape and active conformation of the Dcp1:Dcp2 mRNA decapping complex. In Annual European Magnetic Resonance Meeting (Euromar 2017), p. 72. Annual European Magnetic Resonance Meeting (Euromar 2017), Warszawa, Poland, July 02, 2017 - July 06, 2017. (2017)