Publications of B Hoecker

Toledo-Patiño, S.; Goetz, S.; Shanmugaratnam, S.; Hoecker, B.; Farías-Rico, J.: Molecular handcraft of a well-folded protein chimera. FEBS Letters 598 (11), pp. 1375 - 1386 (2024)

Kröger, P.; Shanmugaratnam, S.; Scheib, U.; Höcker, B.: Fine-tuning spermidine binding modes in the putrescine binding protein PotF. The Journal of Biological Chemistry 297 (6), 101419 (2021)

Wiese, J.; Shanmugaratnam, S.; Höcker, B.: Extension of a de novo TIM barrel with a rationally designed secondary structure element. Protein Science 30 (5), pp. 982 - 989 (2021)

Herud-Sikimić, O.; Stiel, A.; Kolb, M.; Shanmugaratnam, S.; Berendzen, K.; Feldhaus, C.; Höcker, B.; Jürgens, G.: A biosensor for the direct visualization of auxin. Nature 592 (7856), pp. 768 - 772 (2021)

Ferruz, N.; Lobos, F.; Lemm, D.; Toledo-Patino, S.; Farías-Rico, J.; Schmidt, S.; Höcker, B.: Identification and Analysis of Natural Building Blocks for Evolution-Guided Fragment-Based Protein Design. Journal of Molecular Biology 432, pp. 3898 - 3914 (2020)

Toledo-Patiño, S.; Chaubey, M.; Coles, M.; Höcker, B.: Reconstructing the Remote Origins of a Fold Singleton from a Flavodoxin-Like Ancestor. Biochemistry 58 (48), pp. 4790 - 4793 (2019)

Lichtenstein, B.; Höcker, B.: Engineering an AB 5 Protein Carrier. Scientific Reports 8, 12643 (2018)

Lichtenstein, B.; Höcker, B.: Engineering an AB5 Protein Carrier. Scientific Reports 8 (1), 12643 (2018)

Banda-Vázquez, J.; Shanmugaratnam, S.; Rodríguez-Sotres, R.; Torres-Larios, A.; Höcker, B.; Sosa-Peinado, A.: Redesign of LAOBP to bind novel l-amino acid ligands. Protein Science 27 (5), pp. 957 - 968 (2018)

Huang, P.-S.; Feldmeier, K.; Parmeggiani, F.; Fernandez Velasco, D.; Höcker, B.; Baker, D.: De novo design of a four-fold symmetric TIM-barrel protein with atomic-level accuracy. Nature Chemical Biology 12 (1), pp. 29 - 34 (2016)

Farías-Rico, J.; Schmidt, S.; Höcker, B.: Evolutionary relationship of two ancient protein superfolds. Nature Chemical Biology 10 (9), pp. 710 - 715 (2014)

Höcker, B.: Design of proteins from smaller fragments-learning from evolution. Current Opinion in Structural Biology 27, pp. 56 - 62 (2014)

Höcker, B.; Midelfort, K.: Designing protein function: macromolecular design. Journal of Structural Biology 185 (2), p. 135 (2014)

Scheib, U.; Shanmugaratnam, S.; Farías-Rico, J.; Höcker, B.: Change in protein-ligand specificity through binding pocket grafting. Journal of Structural Biology: X 185 (2), pp. 186 - 192 (2014)

Feldmeier, K.; Höcker, B.: Computational protein design of ligand binding and catalysis. Current Opinion in Chemical Biology 17 (6), pp. 929 - 933 (2013)

Höcker, B.: Engineering chimaeric proteins from fold fragments: "hopeful monsters" in protein design. Biochemical Society Transactions 41 (5), pp. 1137 - 1140 (2013)

Maier, M.; Rajendran, C.; Malisi, C.; Fox, N.; Xu, C.; Schlee, S.; Barondeau, D.; Höcker, B.; Sterner, R.; Raushel, F.: Molecular engineering of organophosphate hydrolysis activity from a weak promiscuous lactonase template. Journal of the American Chemical Society 135 (31), pp. 11670 - 11677 (2013)

Malisi, C.; Schumann, M.; Toussaint, N.; Kageyama, J.; Kohlbacher, O.; Höcker, B.: Binding pocket optimization by computational protein design. PLoS One 7 (12), e52505 (2012)

Höcker, B.: A toolbox for protein design. Nature 491 (7423), pp. 204 - 205 (2012)

Shanmugaratnam, S.; Eisenbeis, S.; Höcker, B.: A highly stable protein chimera built from fragments of different folds. Protein Engineering Design and Selection 25 (11), pp. 699 - 703 (2012)