Publications

Braun, J.; Huntzinger, E.; Izaurralde, E.: A molecular link between miRISCs and deadenylases provides new insight into the mechanism of gene silencing by microRNAs. Cold Spring Harbor Perspectives in Biology 4 (12), a012328 (2012)

Braun, J.; Truffault, V.; Boland, A.; Huntzinger, E.; Chang, C.-T.; Haas, G.; Weichenrieder, O.; Coles, M.; Izaurralde, E.: A direct interaction between DCP1 and XRN1 couples mRNA decapping to 5' exonucleolytic degradation. Nature Structural and Molecular Biology 19 (12), pp. 1324 - 1331 (2012)

Rosenwald, M.; Kopee, U.; Keppeler, H.; Sauer, G.; Hennel, R.; Ernst, A.; Blume, K.; Peter, C.; Herrmann, M.; Belka, C. et al.; Schulze-Osthoff, K.; Wesselborg, S.; Lauber, K.: Serum-derived plasminogen is activated by apoptotic cells and promotes their phagocytic clearance. The Journal of Immunology 189 (12), pp. 5722 - 5728 (2012)

Petit, A.-P.; Wohlbold, L.; Bawankar, P.; Huntzinger, E.; Schmidt, S.; Izaurralde, E.; Weichenrieder, O.: The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complex. Nucleic Acids Research (London) 40 (21), pp. 11058 - 11072 (2012)

Vollmer, B.; Schooley, A.; Sachdev, R.; Eisenhardt, N.; Schneider, A.; Sieverding, C.; Madlung, R.; Gerken, U.; Macek, B.; Antonin, W.: Dimerization and direct membrane interaction of Nup53 contribute to nuclear pore complex assembly. EMBO Journal 31 (20), pp. 4072 - 4084 (2012)

Izaurralde, E.: Elucidating the temporal order of silencing. EMBO Reports 13 (8), pp. 662 - 663 (2012)

Kuzuoğlu-Öztürk, D.; Huntzinger, E.; Schmidt, S.; Izaurralde, E.: The Caenorhabditis elegans GW182 protein AIN-1 interacts with PAB-1 and subunits of the PAN2-PAN3 and CCR4-NOT deadenylase complexes. Nucleic Acids Research (London) 40 (12), pp. 5651 - 5665 (2012)

Sauer, E.; Schmidt, S.; Weichenrieder, O.: Small RNA binding to the lateral surface of Hfq hexamers and structural rearrangements upon mRNA target recognition. Proceedings of the National Academy of Sciences of the United States of America 109 (24), pp. 9396 - 9401 (2012)

Eisenbeis, S.; Proffitt, W.; Coles, M.; Truffault, V.; Shanmugaratnam, S.; Meiler, J.; Höcker, B.: Potential of fragment recombination for rational design of proteins. Journal of the American Chemical Society 134 (9), pp. 4019 - 4022 (2012)

Fromm, S.; Truffault, V.; Kamenz, J.; Braun, J.; Hoffmann, N.; Izaurralde, E.; Sprangers, R.: The structural basis of Edc3- and Scd6-mediated activation of the Dcp1:Dcp2 mRNA decapping complex. EMBO Journal 31 (2), pp. 279 - 290 (2012)

Izaurralde, E.: GW182 Proteins Directly Recruit Cytoplasmic Deadenylase Complexes to miRNA Targets. Keysone Symposia: Protein-RNA Interactions in Biology and Disease (C1), Santa Fe, NM, USA (2012)

Milton, C.; Jonas, S.; Hyvönen, M.; Tokuriki, N.; Hollfelder, F.: Exploring Catalytic Promiscuity in the Alkaline Phosphatase Superfamily by Directed Evolution. 26th Annual Symposium of The Protein Society, San Diego, CA, USA (2012)

Braun, J.: Der Mechanismus des microRNA-vermittelten mRNA-Abbaus: Mechanism of microRNA-mediated mRNA Decay. Dissertation, Eberhard-Karls-Universität, Tübingen, Germany (2012)