Publications
_{Molecular Recognition and Catalysis}

Boudrioua, A.; Joiner, J.; Grin, I.; Kronenberger, T.; Korotkov, V.; Steinchen, W.; Kohler, A.; Schminke, S.; Schulte, J.-C.; Pietsch, M. et al.; Naini, A.; Kalverkamp, S.; Hotop, S.-K.; Coyle, T.; Piselli, C.; Coles, M.; Rox, K.; Marschal, M.; Bange, G.; Flieger, A.; Poso, A.; Brönstrup, M.; Hartmann, M.; Wagner, S.: Discovery of synthetic small molecules targeting the central regulator of Salmonella pathogenicity. Science Advances 11 (15), eadr5235 (2025)

Ananevaa, A.; Kantin, G.; Dar’in, D.; Bunev, A.; Ebeling, S.; Herrmann, A.; Hartmann, M.; Kalinin, S.; Bakulina, O.: Catalytic Castagnoli–Cushman reaction-based synthesis of tetrahydroisoquinolone–glutarimide dyads and their evaluation as potential cereblon ligands. Mendeleev Communications 35 (3) (2025)

Piselli, C.: How to isolate channel-forming membrane proteins using the E. coli expression system. Nature Protocols 20 (2), pp. 462 - 479 (2025)

Khuzhakhmetova, L.; Ananeva, A.; Gantin, G.; Dar’in, D.; Bunev, A.; Ebeling, S.; Herrmann, A.; Hartmann, M.; Kalinin, S.; Bakulina, O.: Synthesis of α-(azidomethyl)glutarimide and its applicationin construction of potential Cereblon ligands via the CuAAC reaction. Mendeleev Communications 35 (1), pp. 69 - 72 (2025)

Ullrich, T.; Klimenkova, O.; Pollmann, C.; Lasram, A.; Hatskovska, V.; Maksymenko, K.; Milijaš-Jotić, M.; Schenk, L.; Lengerke, C.; Hartmann, M. et al.; Piehler, J.; Skokowa, J.; ElGamacy, M.: A Strategy to Design Protein-based Antagonists Against Type I Cytokine Receptors. PLOS Biology (accepted)

Schwab, S.; Hu, Y.; van Erp, B.; Kajili, M.; Hartmann, M.; Hernandez-Alvarez, B.; Alva, V.; Boyle, A.; Dame, R.: Histones and histone variant families in prokaryotes. Nature Communications 15 (1), 7950 (2024)

Hu, Y.; Schwab, S.; Deiss, S.; Escudeiro, P.; van Heesch, T.; Joiner, J.; Vreede, J.; Hartmann, M.; Lupas, A.; Hernandez Alvarez, B. et al.; Alva, V.; Dame, R.: Bacterial histone HBb from Bdellovibrio bacteriovorus compacts DNA by bending. Nucleic Acids Research 52 (14), gkae485, pp. 8193 - 8204 (2024)

Selim, K.; Alva, V.: PII-like signaling proteins: a new paradigm in orchestrating cellular homeostasis. Current Opinion in Microbiology 79, 102453 (2024)

Shevalev, O.; Bischof, L.; Sapegin, A.; Bunev, A.; Grigoreva, O.; Kantin , G.; Kalinin, S.; Hartmann, M.: Discovery and characterization of potent spiro-isoxazole-based cereblon ligands with a novel binding mode. European Journal of Medicinal Chemistry 270, 116328 (2024)

Hartmann, M.: TRIM for Tissue Specificity. ACS Medicinal Chemistry Letters 15 (1), pp. 4 - 5 (2024)

Joiner, J.; Steinchen, W.; Mozer, N.; Kronenberger, T.; Bange, G.; Poso, A.; Wagner, S.; Hartmann, M.: HilE represses the activity of the Salmonella virulence regulator HilD via a mechanism distinct from that of intestinal long-chain fatty acids. The Journal of Biological Chemistry 299 (12), 105387 (2023)

Fonseca Lopez, F.; Miao, J.; Damjanovic, J.; Bischof, L.; Braun, M.; Ling, Y.; Hartmann, M.; Lin, Y.-S.; Kritzer, J.: Computational Prediction of Cyclic Peptide Structural Ensembles and Application to the Design of Keap1 Binders. Journal of Chemical Information and Modeling 63 (21), pp. 6925 - 6937 (2023)

Steinebach, C.; Bricelj, A.; Murgai, A.; Sosič, I.; Bischof, L.; Ng, Y.; Heim, C.; Maiwald, S.; Proj, M.; Voget, R. et al.; Feller, F.; Košmrlj, J.; Sapozhnikova, V.; Schmidt, A.; Zuleeg, M.; Lemnitzer, P.; Mertins, P.; Hansen, F.; Gütschow, M.; Krönke, J.; Hartmann, M.: Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs. Current Medicinal Chemistry 66 (21), pp. 14513 - 14543 (2023)

Kuchta, R.; Heim, C.; Herrmann, A.; Maiwald, S.; Ng, Y.; Sosič, I.; Keuler, T.; Krönke, J.; Gütschow, M.; Hartmann, M. et al.; Steinebach, C.: Accessing three-branched high-affinity cereblon ligands for molecular glue and protein degrader design. RSC Chemical Biology 4 (3), pp. 229 - 234 (2023)

Mantovani, O.; Haffner, M.; Selim, K.; Hagemann, M.; Forchhammer, K.: Roles of second messengers in the regulation of cyanobacterial physiology: the carbon-concentrating mechanism and beyond. microLife 4, uqad008 (2023)

Selim, K.; Haffner, M.; Mantovani, O.; Albrecht, R.; Zhu, H.; Hagemann, M.; Forchhammer, K.; Hartmann, M.: Carbon signaling protein SbtB possesses atypical redox-regulated apyrase activity to facilitate regulation of bicarbonate transporter SbtA. Proceedings of the National Academy of Sciences of the United States of America 120 (8), e2205882120 (2023)

Selim, K.; Zimmer, E.: SbtB: der fehlende Sensor für anorganischen Kohlenstoff in Cyanobakterien. Biospektrum 29 (2), pp. 140 - 143 (2023)

Heim, C.; Spring, A.-K.; Kirchgäßner, S.; Schwarzer, D.; Hartmann, M.: Cereblon neo-substrate binding mimics the recognition of the cyclic imide degron. Biochemical and Biophysical Research Communications 646, pp. 30 - 35 (2023)

Heim, C.; Spring, A.-K.; Kirchgäßner, S.; Schwarzer, D.; Hartmann, M.: Identification and structural basis of C-terminal cyclic imides as natural degrons for cereblon. Biochemical and Biophysical Research Communications 637, pp. 66 - 72 (2022)

Krasavin, M.; Adamchik, M.; Bubyrev, A.; Heim, C.; Maiwald, S.; Zhukovsky, D.; Zhmurov, P.; Bunev, A.; Hartmann, M.: Synthesis of novel glutarimide ligands for the E3 ligase substrate receptor Cereblon (CRBN): Investigation of their binding mode and antiproliferative effects against myeloma cell lines. European Journal of Medicinal Chemistry 246, 114990 (2022)